Recent study results conducted by Bélin Poletto Mezzomo et. al, has pegged the Bt toxins and plants with the said Bt gene into deeper controversy.
Bacillus thuringiensis (Bt), a microbiological control agent. It produces entomopathogenic toxins, the insecticidal crystal proteins or simply the Cry proteins namely Cry1Aa, Cry1Ab, Cry1Ac or Cry2A. It function as natural biological control agent. Its application was simplified by incorporating the Bt gene, which produces toxins, to plants, like corn and egg plant. GMO plants gained the ability to produce their own toxin thus worms die after feeding on any plant part.
Bt toxins act as soon as it reached the alkaline stomach of worms, or agricultural pest from the Hymenoptera, Homoptera, Orthoptera, Coleoptera, Diptera and Lepdoptera Orders. Mammalian stomach is acid, so the cry protein effect is expected minimal or generally safe. However, results of this study is speaking the reverse.
“Results showed that the Bt spore-crystals genetically modified to express individually Cry1Aa, Cry1Ab, Cry1Ac or Cry2A can cause some hematological risks to vertebrates, increasing their toxic effects with long-term exposure.”
Authors suggested further studies….
source: Mezzomo BP, Miranda-Vilela AL, Freire IdS, Barbosa LCP, Portilho FA, et al. (2013) Hematotoxicity of Bacillus thuringiensis as Spore-crystal
Strains Cry1Aa, Cry1Ab, Cry1Ac or Cry2Aa in Swiss Albino Mice. J Hematol Thromb Dis 1: 104. doi:10.4172/jhtd.1000104