Would You Consider Getting DengVaxia® Shots? The First Dengue Vaccine.

Perhaps, the tawa-tawa herb is the first dengue medicine known to man. It has been proven by very few scientific studies and thousands of anecdotal literature. I hope it is not true as of date! Pharma companies sure not making money from it. The herb can be grown easily and can be found in the wilds.

It is meant to cure, not prevent. Vaccine does that. The DengVaxia® is the first commercially available dengue vaccine introduce in the market.

According to who.int, DengVaxia® or CYD-TDV is the first dengue vaccine to be licensed. It was first licensed in Mexico in December 2015 for use in individuals 9-45 years of age living in endemic areas. CYD-TDV is a live recombinant tetravalent dengue vaccine developed by Sanofi Pasteur (CYD-TDV), given as a 3-dose series on a 0/6/12 month schedule.

It has various efficacy levels among age groups. Though licensed, it is still a new drug in stage of clinical trials. Earning cash while getting research data is a dirty trick in my opinion. They should have put more effort into it before making the general public their guinea pigs.

The vaccine already reached the Philippine archipelago. The developer together with Watson’s Personal Care Store planned to conduct immunization service which cost 4,000 pesos per shot. Three shots should be given in a year so it is a whooping 12,000 pesos per head. Not much if you belong to middle class, consider the dengue danger and cost of hospitalization.

However, Food and Drug Administration (FDA) prevented the act due to the following reasons. Lack of license to conduct immunization service. Drug safety is not assured. Unauthorized advertisement and promotion last April. It leads to misconception that vaccine is over-the-counter where in fact it is a prescription medicine. The agency further stated, they will revoke the product registration if the two companies continue making violations.

Something feels not right here. Certificate of Product Registration never means you can promote, advertise and administer the vaccine. Separate permits are needed for each purpose. And how come the product was approved for registration if its safety is not assured.

According to FiercePharma.com, the vaccine may do more harm than good if used in low-risk area. They stressed, dengue virus works differently than others. Second attack is expected worse than the first. In case a person receives the vaccine. It will be perceived as first infection, without making the body sick. When the same person acquires the virus naturally, the resulting sickness is expected severe. Thus, the vaccine is recommended only in high-risk areas.

Vaccine is a weak version of virus causing disease. Dengue vaccine is the weak version of dengue virus. By getting the shots, you’ll be getting a weaker version of dengue virus that your body’s immune system can easily fight. It helps produce the necessary antibodies to fight the weak and stronger virus.

Update December 2017

So some of our government officials and drug companies choose the controversial drug over the low cost tawa-tawa. I am sure you have heard about the 3.5 B Dengvaxia controversy by now. It was implemented sometime in 2016 and around 733 thousand people have been vaccinated. I think the actual value before the program stopped has grown significantly.

For whatever reasons it maybe, the authorities stopped the program only now, after almost a year. Why? WHO and the vaccine developer itself clearly stated that it may do more harm than good in some cases. The first even released a statement saying it should be only used in areas where there is proven dengue outbreak. The org never issued any recommendation to Philippines to use such.

Sanofi Pasteur said, severe is not what you think it is. It will not likely  cause death. I am surprised! The disease is a popular life claimer. How can they say “severe dengue” won’t cause death!

About two hours ago from Interaksyon. DOH Secretary confirmed the case of 12-year-old student from Tarlac who suffered severe dengue case after being injected with DengVaxia. It brought dengue to student instead of protecting her from the dreaded disease.

Another suspected case was reported from Batangas province. A child who belongs to the first group of vaccination also contracted the disease.

Tawa Tawa, Luya and Babana are Possible Dengue Cures | not prohibited but not yet recommended

Tawa tawa, luya and banaba are possible cures for dengue but need intensive studies before it can be promoted to general public. Authorities are not promoting it but also not discouraging its use. They are playing safe I guess. They want to help but also never want to face the blame in the end.

All three herbal medicines are currently subject to various verification studies of institutions like Department of Science and Technology (DOST) and UERM. Experts added that proving efficacy of a herbal medicine really entails hard work.

Ten herbal medicines are currently registered to Food and Drug Administration(FDA). The medicinal plants were subjected under series of long intensive studies before got  approved. Let’s hope the three mentioned plants are next in line.

Latest Department of Health (DOH) list recorded 42,407 dengue cases for the first six months of year 2013.

via gma 24 oras

You May Now Take Tawa Tawa to Cure Dengue

Recently the tawa tawa plant was featured again, in GMA7’s Kape at Balita and 24 Oras.

As per request by the Department of Health (DOH), the University of the East – Ramon Magsaysay Memorial Medical Center conducted a one year study, involving 100 persons, to know if the tawa tawa is effective against dengue.

Study results will go on public on June 2013 via scientific conference. When and where the announcement is scheduled is not clear. However, Dr. Josefina Carlos gave a glimpse of their findings.

The herb could be found almost everywhere, it is free and would be very useful if found effective, and with no negative side effects. Since year 1950, there has historical and anecdotal experiences about tawa tawa’s action against dengue, here and in other countries. It has no noted side effects, thus could be taken safely in case dengue strikes.
Tawa tawa dosage is the problem. How much and how often it should be taken is not established yet.

The herb tawa tawa is also being studied by other universities and institutions like UST and Saint Luke’s

Yet Another Herbal Cure for Dengue Virus

I downloaded five free food biochemistry publications. I think those five are good enough as choices. My professor is going to approve one for my oral report.

Among the five articles, I prefer the one talking about the vegetable which is able to fight dengue viral infection.

This illness is a global problem and so far no real drug has been established as cure. The popular alternative medicine is the tawa tawa or gatas gatas. No sufficient studies yet about its efficacy. It could not be recommended by authorities and could not be packaged by pharmaceutical companies.

The publised article is entitled: The Inhibitory Actions of Houttuynia Cordata
Aqueous Extract on Dengue Virus and
Dengue-Infected Cells

by: vijittra leardkamolkarn , wipawan sirigulpanit1, chayakom phurimsak,
supeecha kumkate, lukana himakoun and bungorn sripanidkulchai

The short ABSTRACT as I read.

The antiviral activities of Houttuynia cordata (H. cordata) aqueous extract against
dengue virus serotype 2 (DEN-2), strain 16681, were evaluated in this study. The
results showed that pre- and post-incubation of H. cordata extract (10–100 µg/mL)
with HepG2 cells significantly reduced intracellular DEN-2 RNA production corre-
lating with the decrease in dengue protein expression. In the direct blocking mode,
the extract bound with DEN-2 and strongly inhibited the intracellular viral RNA
replication with an effective dose (EC50) of 0.8 µg/mL. Concentrations as low as
10–40 µg/mL of H. cordata extract also exhibited protective effect on virion release
from infected LLC-MK2 cells. High-performance liquid chromatography analysis of
H. cordata extract indicated that hyperoside was the predominant bioactive com-
pound, and was likely to play a role in this inhibition. The extract was also shown to
have no genotoxic effect on human blood cells.

The article is a 6-pages pdf document. Most terms are technical and cannot be understand easily by an average person like me. However, it is clearly stated that  Houttuynia cordata (lizard tail or chameleon plant) is effective in fighting dengue virus.

The complete study copy can be found on Wiley Online Library.

Based on wikipedia, the vegetable looks like this.

lizard tail chameleon plant

Update: Tawa Tawa and Ginger Extract can Kill Dengue Virus

fresh tawa tawa herb

The initial study result about tawa tawa herb was very promising. And there is more, the spicy ginger gave a promising result too. Laboratory trials showed that 99 percent of dengue viral plaque can be killed by tawawa extract. Ginger extract can kill 56 percent. For the advancement, it will be tested in animals.

Other medicinal herbs included in the study are:

centella / takip suso/ takip kuhol

The study is being done by the Saint Lukes Medical Center through the funding of the Department of Science and technology (DOST).

The Department of Health (DOH) stated: Taking tawa tawa herb as dengue cure is not yet recommended. It is still best to go to hospital as early as possible for treatment.

The Guppy Fish for Dengue Fight / Prevention?

The news about guppy fish and dengue was flashed on TV5 Aksyon. I got excited cause the news said that it was a new discovery for fighting dengue. I patiently wait for the segment. guppy fish for dengue fighting

The solution came from Cordillera Province. Its about the small guppy fishes. One full grown guppy fish has the capacity to eat one drum of water with lots of mosquito larvae. It was introduced to province as control for malaria.

The Department of Health is now studying the potency of guppy fish in controlling dengue causing  mosquitoes. The department plan to pilot test the fish in Baguio City this coming year 2012. If it is a success, guppy fishes will be distributed nationwide.

I thought it could be eaten like tawa tawa herb. Guppy fish is for prevention and prevention is always the best.

I still wonder why they are not studying the potency of tawa tawa herb.

photo courtesy of nevit